Following their 17-2 win over LA Harbor College in their homecoming game, Pierce took a trip to Santa Maria to face the conference leaders, Hancock College.
It was a close first half with the teams going into halftime 17-7, but things went downhill in the second half as the Brahmas lost 45-13.
The defense which only allowed a safety against the Seahawks went behind early as Maurice Jones scored his first touchdown of the game on a nine-yard run.
In the second quarter, Edgar Zacarias kicked a 20-yard field goal after Eddie Battle fumbled near the end zone.
Pierce responded with a touchdown from Kevin Ascencio on a 34-yard run with the extra point being good.
With less than four minutes in the half, Hancock would restore a 10-point lead. Jerome Afe catching an eight-yard pass from Matt Garcia.
At the start of the second half, the Bulldogs went all offense. Desmond Newkirk scored on a one-yard run and Jones got his second TD of the game.
In the fourth quarter, Battle scored on a 63-yard run. Qualik Davies wrapped things up for Hancock, making the score 45-7.
Jakobe Harvey scored for Pierce in the final minutes of the game.
With the loss, Pierce dropped to 2-7 on the season, while Hancock improved to 7-2.
The Brahmas wrap their season up on Saturday when they host Santa Monica College. Kickoff is scheduled for 6 p.m.